They got together at Stan Lee's LA Comic Con, 21 years after the show first hit screens in the mid nineties.
Melissa Joan Hart, who played the lead role in the beloved children's show, joined cast members on stage for a special appearance.
The actress, who was 20 when the first series of the show aired in 1996, was instantly recognisable as she lined-up alongside some of the main cast.
Both Beth Broderick and Caroline Rhea, who played the teen witch's aunts Zelda and Caroline, were in attendance, as was voice actor Nick Bakay who is famed for his voice role as Sabrina's sassy feline companion, Salem.
Melissa's old on-screen flame Nate Richert who played Harvey Kinkle looked very different to his alter ego with a goatee beard.
Now 39-years-old, Nate has largely ditched acting to concentrate on his music career.
Also making an appearance were the likes of Alimi Ballard (Quizmaster Albert), Soleil Moon Frye (Roxie King), Elisa Donovan (Morgan Cavanaugh).
Clearly delighted at being reunited with the friends she spent the best part of a decade working with, Melissa shared a number of happy snaps of the group enjoying themselves at the event.
Fun to see so many #witches, #wizards and #talking cats in one place. I will be eternally grateful to have been a part of #SabrinatheTeenageWitch. As if no time had passed at all we will always be part #Spellman I will happily answer to #AuntHilda forever and when you tell me that you grew up watching me it makes me cry too. In a good way. #BestWitches #HappyHalloween from #AuntHilda Loved seeing everyone even if @MoonFrye and I did get lost at #comic con #@melissajoanhart @bethbroderick @nate.richert #NickBakay We missed you #JennaLeighGreen
She titled one Instagram group shot: "Missing some of our friends but having fun catching up after 20 years." Possibly referencing the fact that some other all-star castmembers, such as Martin Mull were not in attendance.
Since the show ended in 2003 Melissa has continued with her acting career and most recently starred in sit-com Melissa and Joey alongside Joey Lawrence for five years between 2010-2015.
She had her first taste of the limelight in Clarissa Explains It All, which aired from 1991-1994 - though she was already a seasoned child actor by that point.