It's set to close on the 21st April.
Marks & Spencer have confirmed their store in Keighley will close in April.
It was one a number earmarked for closure by the end of 2018. In total 14 will be shut nationwide.
Andrew Crooks, Head of Region for Yorkshire, said: “Proposing to close the Keighley store was a difficult but necessary decision, and over the past few weeks we’ve been consulting with our colleagues. Following this rigorous process, the decision has been made to close the store on 21st April."
Andrew went on to say: "We’d like to thank our customers at the store and the local community for the feedback they’ve given us over the last few weeks. We hope to see lots of the customers continuing to shop at our other stores in the area, as well as on M&S.com.”